Abstract: The knock prediction of two-stroke ignition aviation kerosene piston engines is studied in this paper. Based on 3-Arrhenius equation, this paper proposes a two-component blended knock prediction model. According to the experimental data of aviation kerosene combustion, a combustion model of aviation kerosene is developed and checked by using GT-Power software. The temperature of the end mixture gas required by the knock prediction model is obtained through one-dimensional performance simulation. The prediction performance of the blended knock prediction model and the single knock prediction model is evaluated through the engine knock test data. The results show that the standard errors between the predicted knock onset angle and the experimental knock onset angle are 1.19°CA and 3.23°CA respectively for the blended knock prediction model and single knock prediction model. The blended knock prediction model can identify the low-pressure region at the initial stage of combustion, and it has a good response to the sudden increase of pressure in the cylinder during the knock cycle, which shows a good knock prediction performance.