Abstract: The high average cost and the low overall profit margin of China’s logistics industry are not conducive to the sustainable development of the industry and online consumer market. This paper proposes a primary centralized logistics operation based on freight consolidation to cut costs and improve efficiency in the logistics industry. It explores the efficient and low-cost operation mode of express transportation logistics, conforming to China’s actual conditions. First, this paper takes logistics and customer contact outlets as the starting point to build a bi-level programming model to cut costs and increase profits. Then, the game analysis is made on whether the logistics providers and users choose the strategy built by this model. Finally, the data of express outlets are empirically analyzed by seeking the the optimal solution of the strategy model through the peak searching algorithm. The time constraint in the implementation of the centralized strategy is further improved according to the solution of the shortest path problem. Our theoretical and empirical results show the centralization strategy of logistics outlets improves efficiency and reduces costs. The peak searching algorithm and strategy game effectively address the problems of the bi-level programming model in logistics optimization.