重庆理工大学学报(自然科学) ›› 2023, Vol. 37 ›› Issue (5): 318-323.

• 药学·生物工程 • 上一篇    下一篇

经 IDDS联合给药治疗难治性癌痛患者的药学监护

鞠 桦,蒋为薇,石 磊,楚 磊,朱丽蓉,林治华   

  1. 1.重庆理工大学 药学与生物工程学院,重庆 400054; 2.重庆医科大学附属第二医院,重庆 400010; 3.重庆市第十三人民医院,重庆 400053;4.重庆市第九人民医院,重庆 400700)
  • 出版日期:2023-06-21 发布日期:2023-06-21
  • 作者简介:鞠桦,女,主管药师,主要从事临床药学、医院药学研究,Email:280620921@qq.com;通信作者 林治华,男,博士, 教授,主要从事药物设计与合成研究,Email:zhlin@cqut.edu.cn。

Pharmaceutical care of patients with refractory cancer pains treated with IDDS

  • Online:2023-06-21 Published:2023-06-21

摘要: 为探讨疼痛专科临床药师在植入鞘内药物输注系统(intrathecaldrugdeliverysys tems,IDDS)治疗难治性癌痛病例中的作用,临床药师参与 1例植入 IDDS治疗难治性癌痛患者 的临床药物治疗,评估患者疼痛的性质,协助临床医师从镇痛药物的遴选、药物剂量、药品不良 反应、相互作用等方面制定个体化用药方案,密切关注患者的镇痛方案疗效及并发症状,为临床 提供药物合理性建议,为患者实施药学监护并提供用药教育。治疗结果显示,患者疼痛控制满 意,药物治疗全面优化,未发生严重药物不良反应,说明疼痛专科临床药师通过对癌痛患者进行 动态、全面的疼痛评估,参与镇痛方案制定及不良反应监测,可从合理用药的角度协助优化鞘内 镇痛用药方案,提高患者用药依从性,保障患者用药安全。

关键词: IDDS, 难治性癌痛, 药学监护, 临床药师

Abstract: Objective: This paper aims to explore the role of clinical pharmacists of pain specialty in the treatment of refractory cancer pains by implanting intrathecal drug delivery systems (IDDS). Methods: A clinical pharmacist participates in a case of clinical treatment of a patient with refractory cancer pains by implanting IDDS, evaluates the nature of the patient’s pains, assists the doctor to formulate an individualized dosing plan from the aspects of analgesic drug selection, drug dose, adverse drug reactions and interactions, and closely observes the treatment effect of the patient’s pains and the concurrent symptoms. In this way, this paper puts forward reasonable suggestions for the clinical drugs, and carries out pharmaceutical care for the patient and provides medication education. Results: The patient’s pain control is satisfactory, and the drug treatment is comprehensively optimized without any serious adverse drug reactions. Conclusion: By conducting dynamic and comprehensive pain assessment on cancer pain patients, the clinical pharmacist of pain specialty participates in analgesic plan formulation and adverse reaction monitoring. Therefore, it is advised to help optimize the intrathecal analgesic medication plan from the perspective of rational medication, improve the medication compliance of patients and ensure their medication safety

中图分类号: 

  • R737.14