Abstract: Tire wear not only affects vehicle acceleration, safety, handling and many other performances, but also generates wear particles that pollute the environment. To explore the relationship between tire wear performance and grounding characteristics, research is conducted on 205/55R16 tire. Different tread structure parameters are designed. Meanwhile, the friction energy loss rate is selected as the wear performance evaluation index, and the grounding characteristic parameters are obtained by finite element method. The linear regression analysis method is employed to build the regression equation between the friction energy loss rate and the grounding characteristic parameters. Then, the effects of different tread structures parameters on the grounding characteristics and wear performance are studied. The results show the regression equation has high fitting accuracy, which can predict the tire wear performance through the grounding characteristic parameters. This method may provide references for tire wear performance improvement and tread structure optimization.